Managing Skin Cancer by Eggert Stockfleth Theodore Rosen & Stephen Shumack

Author:Eggert Stockfleth, Theodore Rosen & Stephen Shumack
Language: eng
Format: epub
Publisher: Springer Berlin Heidelberg, Berlin, Heidelberg

8.2.1.5 Adult T-Cell Leukemia/Lymphoma

Adult T-cell leukemia/lymphoma (ATLL) is a malignancy known to be associated with HTLV-1 infection. Clinically, ATLL most often presents with leukemic, organ, and skin involvement (acute form), but there are cases where it will present with skin lesions alone that mimic MF (smouldering form) [60]. Histology of the affected skin reveals infiltrates of pleomorphic T-lymphocytes (commonly CD3+, CD4+, CD25+, and CD8−) with epidermotropism and again can be consistent with MF histology [60].

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